Before we go into the ending of Madame Web, it’s important to address a major question fans have been asking — is Spider-Man part of the movie? Well, the answer is yes, but with a twist. Adam Scott plays Ben Parker, better known as Uncle Ben.
He serves as a paramedic alongside Cassandra. We also meet his sister, Mary Parker (played by Emma Roberts), who is pregnant in the film. The child she’s carrying is Peter Parker, who will one day become Spider-Man.

Though the baby isn’t directly named, it’s clear this is Peter Parker. It’s still unclear which version of Peter this is, but considering the timeline, it seems to align with Tom Holland’s portrayal.
The choice to set the film in 2003 isn’t directly related to Peter’s origin but rather more focused on Cassandra’s backstory. Director SJ Clarkson explained this decision, saying it connects to Cassandra’s origins from the 1970s.
Madame Web Ending Explained
Now, let’s take a closer look at Madame Web. After days of running from danger, Cassandra leaves her friends Julia, Anya, and Mattie with Ben Parker and her sister Mary, who is pregnant, while she goes to the Peruvian Amazon rainforest in search of answers.
She learns that Ezequiel had been in the Amazon with her mother, Constance, researching spiders just before her death. Ezequiel shot Constance while she was pregnant to steal a special spider with unique powers.
The Arañas, a group of super-powered people from the Amazon, tried to save Constance by injecting the spider’s powers into her, but only baby Cassandra survived.
Before leaving the Amazon, Cassandra is left with an insightful message: “The moment you take on the responsibility, great power will come.” It’s a phrase very close to the famous “With great power comes great responsibility.”
Back in the city, Mary’s waters break, sending Ben and the girls rushing to the hospital. By leaving the house, they become visible to the city’s cameras, which allows Ezequiel’s accomplice, Amaria, to track their location. Cassandra reaches the Parkers’ home, only to find they’ve gone missing.
She has a vision of them in danger and decides to take an ambulance, racing to their rescue. By the time she arrives, Ezequiel has caused a massive traffic disruption to corner the teenagers. Cassandra crashes the ambulance into him to stop him, but this doesn’t deter Ezequiel.
Ben and Mary are left behind on their way to the hospital, and Cassandra, along with Julia, Anya, and Mattie, heads to an abandoned warehouse to escape. It’s here that Cassandra begins to understand her powers better.
Using her clairvoyance, she sets up a plan to distract Ezequiel with multiple explosions while they are airlifted by helicopter. However, Ezequiel quickly catches up with them, as he’s far too fast and dangerous.
Cassandra Embraces Her Power
In a critical moment, when all seems lost, Cassandra realizes she can be just as lethal as her enemies. She taps into her full power, splitting into four versions of herself to save the others from their life-threatening situations while confronting Ezequiel.

“The girls were never your future. I was,” Cassandra tells him, using her knowledge of the future to place him in the path of a collapsing light sign. She defeats him, but the sign crashes down, pulling Cassandra into the water, and she begins to drown, with a piece of the sign injuring her eyes.
The girls manage to rescue her, but it’s almost too late. Cassandra is not breathing. With the CPR lessons she taught them earlier in the movie, Julia, Anya, and Mattie work together to bring Cassandra back to life. Their quick thinking and teamwork save her.
At the hospital, Mary has given birth, and Cassandra is alive and well, though she has permanently lost her sight due to the injuries to her eyes. The three girls stay by her side in the hospital. When a nurse tells them only family members are allowed, Cassandra simply says, “They’re mine.”
Cassandra’s New Path
Sometime later, Cassandra is seen back at home, now in a wheelchair and wearing sunglasses, a nod to her comic book origins. She’s also more confident in her abilities and proudly declares, “I can see better than I ever have,” showcasing her clairvoyant powers.
Reflecting on the journey of the three young women, she remarks, “I can see you standing up for what you believe. Never giving up.” These girls are now beginning their journey to become Spider-Women: Martha ‘Mattie’ Franklin, Anya Corazón, and Julia Carpenter.
In the final moments of the movie, we catch a glimpse of the future, where they’re suited up as superheroes, standing next to Cassandra, who now wears her red suit. As she stands with them, Cassandra says, “Whatever the future holds, we’ll be ready.”